Source: | Mouse | Gene Id: | 12490 |
Isotype: | IgG1 | Swiss Prot: | Q64314 |
purity: | Affinity chromatography |
Background: |
CD34 is a transmembrane glycoprotein with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells, endothelial cells and some fibroblasts. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is highly expressed on hematopoietic progenitors, as well as on endothelial cells. CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence. |
Reactivity | Human |
Tested applications | WB IHC ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 41 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human CD34 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CD34 |
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