GFI1 Mouse Monoclonal Antibody
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AMM2672-61 50ul 1500.00 In Stock
AMM2672-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 2672
Isotype: IgG1 Swiss Prot: Q99684
purity: Affinity chromatography
Background:
This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.Expression of GFl1 ranges from the hematopoietic and lymphoid system, to sensory epithelia, lung and parts of the CNS.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 45 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A purified recombinant fragment of human GFI1 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym SCN2, GFI-1, ZNF163, FLJ94509, GFI1
This product is for research use only, not for diagnostic or therapeutic use!

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