| No | Size | Price | Availability | |
| AMM23118-61 | 50ul | 1500.00 | In Stock |  |
| AMM23118-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 23118 |
| Isotype: | IgG1 | Swiss Prot: | Q9NYJ8 |
| purity: | Affinity chromatography |
| Background: |
| The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. |
| Reactivity | Human |
| Tested applications | WB ELISA FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 80 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human TAB2 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CHTD2, FLJ21885, KIAA0733, MAP3K7IP2, TAB2 |
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