| No | Size | Price | Availability | |
| AMM9448-61 | 50ul | 1500.00 | In Stock |  |
| AMM9448-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 9448 |
| Isotype: | IgG1 | Swiss Prot: | O95819 |
| purity: | Affinity chromatography |
| Background: |
| a Ser/Thr kinase of the STE20 subfamily. May play a role in the response to environmental stress and cytokines such as TNF-alpha. May interact with the SH3 domain of the adapter proteins Nck. Binds, via its CNH regulatory domain, to the N- terminal region of SPG3A. Upregulated in primary tumors and tumor cell lines. Required for anchorage-independent growth and ras-dependent focus formation in multiple cell lines. 5 isoforms of the human protein are produced by alternative splicing. |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 142 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A purified recombinant fragment of human MAP4K4 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | EC 2.7.11.1, HPK/GCK-like kinase HGK, M4K4, MAP4K4, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, Nck interacting kinase, hepatocyte progenitor kinase-like/germinal center kinase-like kinase, mitogen-activated protein kinase kinase kinase |
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