Source: | Mouse | Gene Id: | 2046 |
Isotype: | IgG1 | Swiss Prot: | P29322 |
purity: | Affinity chromatography |
Background: |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 111 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A purified recombinant fragment of human EphA8 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EC 2.7.10.1, EEK, EPH-and ELK-related kinase, Ephrin type-A receptor 8 precursor, HEK3, KIAA1459, Tyrosine-protein kinase receptor EEK, kinase EphA8 |
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