| No | Size | Price | Availability | |
| AMM5159-61 | 50ul | 1500.00 | In Stock |  |
| AMM5159-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 5159 |
| Isotype: | IgG1 | Swiss Prot: | P09619 |
| purity: | Affinity chromatography |
| Background: |
| Platelet-derived growth factor receptor, beta polypeptide, also known as PDGFRB, PDGFRbeta or CD140B. It is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. This family exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor α (PDGFRα) and PDGF receptor beta (PDGFRbeta). These growth factors are mitogens for cells of mesenchymal origin. PDGFRB is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. |
| Reactivity | Human, Mouse |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 190 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A purified recombinant fragment of human PDGFRbeta expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | JTK12, PDGFR, CD140B, PDGFR1, PDGFRB |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved. 
