| No | Size | Price | Availability | |
| AMM1107-61 | 50ul | 1500.00 | In Stock |  |
| AMM1107-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 1107 |
| Isotype: | IgG1 | Swiss Prot: | Q12873 |
| purity: | Affinity chromatography |
| Background: |
| This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |
| Reactivity | Human, Mouse |
| Tested applications | WB IHC ELISA ICC FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 226 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human CHD3 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CHD3, Chromodomain helicase-DNA-binding protein 3, Mi-2 autoantigen 240 kDa protein, Mi2-alpha |
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