Source: | Mouse | Gene Id: | 3855 |
Isotype: | IgG1 | Swiss Prot: | P08729 |
purity: | Affinity chromatography |
Background: |
CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. |
Reactivity | Human |
Tested applications | WB ELISA FC |
Clonality | Monoclonal Antibody |
Calculated MW | 51 kDa |
Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human CK7 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | KRT7, cytokeratin 7 |
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