Source: | Mouse | Gene Id: | 931 |
Isotype: | IgG1 | Swiss Prot: | P11836 |
purity: | Affinity chromatography |
Background: |
CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1. |
Reactivity | Human |
Tested applications | IHC ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 33 kDa. |
Recommended Dilutions |
IHC 1:200-1:1000
ICC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human CD20 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | B1, S7, Bp35, CD20, MS4A2, LEU-16, MGC3969, MS4A1 |
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