NME1 Mouse Monoclonal Antibody
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AMM4830-61 50ul 1500.00 In Stock
AMM4830-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 4830
Isotype: IgG1 Swiss Prot: P15531
purity: Affinity chromatography
Background:
non-metastatic cells 1,protein,with a nm23 nucleoside diphosphate kinase gene family,involved in the phosphorylation of nucleoside diphosphates,with a reduced expression in tumor progression to the metastatic phenotype,mutated in agressive neuroblastoma,expressed in lung carcinoma cell lines not in normal lung,pyrimidine biosynthetic pathway. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. Has tumor metastasis-suppressive capacity.Tissue specificity: Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.
Reactivity Human
Tested applications WB IHC ELISA ICC FC
Clonality Monoclonal Antibody
Calculated MW 17 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
Immunogen A purified recombinant fragment of human NME1 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym NB, AWD, NBS, GAAD, NM23, NDPKA, NDPK-A, NM23-H1, NME1
This product is for research use only, not for diagnostic or therapeutic use!

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