| No | Size | Price | Availability | |
| AMM7704-61 | 50ul | 1500.00 | In Stock |  |
| AMM7704-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 7704 |
| Isotype: | IgG1 | Swiss Prot: | Q05516 |
| purity: | Affinity chromatography |
| Background: |
| This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. Tissue specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung. |
| Reactivity | Human |
| Tested applications | WB ELISA ICC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 74 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human ZBTB16 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | PLZF, ZNF145, ZBTB16 |
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