Source: | Mouse | Gene Id: | 5753 |
Isotype: | IgG1 | Swiss Prot: | Q13882 |
purity: | Affinity chromatography |
Background: |
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 52 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A purified recombinant fragment of human PTK6 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Breast tumor kinase, EC 2.7.10.2, PTK6, Tyrosine-protein kinase 6, Tyrosine-protein kinase brk |
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