Survivin Mouse Monoclonal Antibody
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AMM332-61 50ul 1500.00 In Stock
AMM332-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 332
Isotype: IgG1 Swiss Prot: O15392
purity: Affinity chromatography
Background:
Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 16 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A purified recombinant fragment of human Survivin expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym API4, EPR-1, BIRC5
This product is for research use only, not for diagnostic or therapeutic use!

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