| No | Size | Price | Availability | |
| AMM4982-61 | 50ul | 1500.00 | In Stock |  |
| AMM4982-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 4982 |
| Isotype: | IgG1 | Swiss Prot: | O00300 |
| purity: | Affinity chromatography |
| Background: |
| The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. |
| Reactivity | Human |
| Tested applications | WB ELISA ICC FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 60 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
ICC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human TNFRSF11B expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Tumor necrosis factor receptor superfamily member 11B [Precursor], Osteoprotegerin, Osteoclastogenesis inhibitory factor, TNFRSF11B, OCIF, OPG |
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