Source: | Mouse | Gene Id: | 4090 |
Isotype: | IgG1 | Swiss Prot: | Q99717 |
purity: | Affinity chromatography |
Background: |
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo; lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous. |
Reactivity | Human, Rat |
Tested applications | WB IHC ELISA ICC FC |
Clonality | Monoclonal Antibody |
Calculated MW | 52 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human SMAD5 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Dwfc, JV5-1, MADH5, DKFZp781C1895, DKFZp781O1323, SMAD5 |
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