TBL1X Mouse Monoclonal Antibody
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AMM6907-61 50ul 1500.00 In Stock
AMM6907-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 6907
Isotype: IgG1 Swiss Prot: O60907
purity: Affinity chromatography
Background:
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Reactivity Human, Monkey
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 62 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A purified recombinant fragment of human TBL1X expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym EBI, TBL1, SMAP55, TBL1X
This product is for research use only, not for diagnostic or therapeutic use!

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