| No | Size | Price | Availability | |
| AMM5604-61 | 50ul | 1500.00 | In Stock |  |
| AMM5604-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 5604 |
| Isotype: | IgG1 | Swiss Prot: | P36507 |
| purity: | Affinity chromatography |
| Background: |
| MAP2K2, also called MEK2, it is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB ELISA ICC FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 44 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
ICC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human MAP2K2 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | MEK2, MKK2, MAPKK2 |
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