Source: | Mouse | Gene Id: | 57626 |
Isotype: | IgG1 | Swiss Prot: | Q9NR64 |
purity: | Affinity chromatography |
Background: |
The mammalian Kelch like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin organizing proteins. Based on the presence of anti sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), |
Reactivity | Human |
Tested applications | WB ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 82 kDa |
Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human KLHL1 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MRP2, FLJ30047, KIAA1490, KLHL1 |
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