Source: | Mouse | Gene Id: | 640 |
Isotype: | IgG1 | Swiss Prot: | P51451 |
purity: | Affinity chromatography |
Background: |
Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response . |
Reactivity | Human |
Tested applications | WB ELISA ICC FC |
Clonality | Monoclonal Antibody |
Calculated MW | 58 kDa |
Recommended Dilutions |
WB 1:500-1:2000
ICC 1:200-1:1000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human BLK expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EC 2.7.10.2B lymphocyte kinasep55-BLK |
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