| Source: | Rabbit | Gene Id: | 69110 | 
| Isotype: | IgG | Swiss Prot: | Q99593 | 
| purity: | Affinity purification | 
| Background: | 
| This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene. | 
| Reactivity | Human | 
| Tested applications | WB IHC ELISA IF ICC | 
| Clonality | Polyclonal Antibody | 
| Calculated MW | 50 kDa | 
| Recommended Dilutions | WB 1:100-1:500 IHC 1:100-1:500 IF 1:100-1:500 ICC 1:100-1:500 | 
| Immunogen | A synthetic peptide derived from human TBX5 | 
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | HOS | 
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