| No | Size | Price | Availability | |
| ARP821-31 | 50ul | 1500.00 | In Stock |  |
| ARP821-31 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 821 |
| Isotype: | IgG | Swiss Prot: | P27824 |
| purity: | Affinity purification |
| Background: |
| Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. Calnexin was first identified as being involved in the assembly of murine class I histocompatibility molecules (1,2). Calnexin is a calcium-binding protein embedded in the ER membrane that retains the newly synthesized glycoproteins inside the ER to ensure proper folding and quality control (3-5). The specificity of calnexin for a subset of glycoproteins is defined by a lectin site, which binds an early oligosaccharide intermediate on the folding glycoprotein (5). |
| Reactivity | Chicken, Cow, Horse, Human, Mouse, Rabbit, Rat |
| Tested applications | WB IHC ELISA IP IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | 69 kDa |
| Recommended Dilutions |
WB 1:100-1:500
IHC 1:100-1:500
IF 1:100-1:500
|
| Immunogen | A synthetic peptide derived from human CANX |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Calnexin, CNX, FLJ26570, IP90, P90 |
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