| No | Size | Price | Availability | |
| ARP2033-31 | 50ul | 1500.00 | In Stock |  |
| ARP2033-31 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2033 |
| Isotype: | IgG | Swiss Prot: | Q09472 |
| purity: | Affinity purification |
| Background: |
| EP300: E1A binding protein p300. This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC ICC |
| Clonality | Polyclonal Antibody |
| Calculated MW | 264 kDa |
| Recommended Dilutions |
WB 1:100-1:400
IHC 1:50-1:200
ICC 1:100-1:500
|
| Immunogen | A recombinant Protein of human EP300 |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | p300, KAT3B, RSTS2 |
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