Source: | Rabbit | Gene Id: | 9063 |
Isotype: | IgG | Swiss Prot: | O75928 |
purity: | Affinity chromatography |
Background: |
PIAS2 Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing may vary depending upon the biological context and the PIAS2 isoform studied. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Polyclonal Antibody |
Calculated MW | 68 kDa |
Recommended Dilutions |
WB 1:500-1:3000
|
Immunogen | A synthetic peptide derived from human PIAS2 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | Androgen receptor-interacting protein 3, ARIP3, DAB2-interacting protein, DIP, E3 SUMO-protein ligase PIAS2, MGC102682, miz, Miz1, Msx-interacting zinc finger protein, Msx-interacting-zinc finger, PIAS-NY protein, PIAS2, PIASX, PIASX-ALPHA, PIASX-BETA, P |
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