Source: | Rabbit | Gene Id: | 10401 |
Isotype: | IgG | Swiss Prot: | Q9Y6X2 |
purity: | Affinity chromatography |
Background: |
PIAS3 Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. Belongs to the PIAS family. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 68 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human PIAS3 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | E3 SUMO-protein ligase PIAS3, FLJ14651, PIAS3, Protein inhibitor of activated STAT protein 3, protein inhibitor of activated STAT, 3, zinc finger, MIZ-type containing 5, ZMIZ5 |
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