Source: | Rabbit | Gene Id: | 51667 |
Isotype: | IgG | Swiss Prot: | Q9Y5A7 |
purity: | Affinity chromatography |
Background: |
NYREN18 Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8 and its conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2. Induced by beta and gamma interferons. Directly interacts with NEDD8 and PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome. |
Reactivity | Human, Mouse |
Tested applications | WB IHC |
Clonality | Polyclonal Antibody |
Calculated MW | 70 kDa |
Recommended Dilutions |
WB 1:500-1:3000
IHC 1:50-1:200
|
Immunogen | A synthetic peptide derived from human NYREN18 |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | BS4, NEDD8 ultimate buster 1, NEDD8 ultimate buster-1, Negative regulator of ubiquitin-like proteins 1, NUB1, NUB1L, NY-REN-18 antigen, NYREN18, Renal carcinoma antigen NY-REN-18 |
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