
| Source: | Rabbit | Gene Id: | 4286 |
| Isotype: | IgG | Swiss Prot: | O75030 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Polyclonal Antibody |
| Calculated MW | 59kDa |
| Recommended Dilutions |
WB 1:500 - 1:2000
|
| Immunogen | A recombinant protein of human MITF |
| Storage | Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | MITF,MI,WS2A,bHLHe32 |
沪ICP备15003525号-1 Copyright ©, 2013-2022, Yihyson All Rights Reserved.