Source: | Rabbit | Gene Id: | 7299 |
Isotype: | IgG | Swiss Prot: | P14679 |
purity: | Affinity purification |
Background: |
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008] |
Reactivity | Human, Mouse, Rat |
Tested applications | WB IHC IF |
Clonality | Polyclonal Antibody |
Calculated MW | 60kDa |
Recommended Dilutions |
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
|
Immunogen | A recombinant protein of human TYR |
Storage | Store at -20oC (regular) or -80oC (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Synonym | CMM8, OCA1A, OCAIA, SHEP3 |
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