| Source: | Mouse | Gene Id: | 1906 | 
| Isotype: | IgG1 Kappa | Swiss Prot: | P05305 | 
| purity: | Affinity purification | 
| Background: | 
| EDN1, also named as Endothelin-1, PPET1 and ET-1, belongs to the endothelin/sarafotoxin family. Endothelins are endothelium-derived vasoconstrictor peptides. Emerging basic science, and animal and human data all suggest that EDN1 is a potentially important contributor in the pathobiology of fibrosing disorders, including those that affect the lung. | 
| Reactivity | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Guinea pig | 
| Tested applications | IHC ELISA IF | 
| Clonality | Monoclonal Antibody | 
| Calculated MW | 2.5 kDa | 
| Recommended Dilutions | IHC 1:100-1:500 IF 1:100-1:500 | 
| Immunogen | A synthetic peptide derived from human EDN11(CSCSSLMDKECVYFCHLDIIW Disulfide bridges C1-C15, C3-C11) | 
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | EDN1,ET1,HDLCQ7 | 
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