| No | Size | Price | Availability | |
| ARM3014P-23C | 50ul | 1500.00 | In Stock |  |
| ARM3014P-23C | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3014 |
| Isotype: | IgG | Swiss Prot: | P16104 |
| purity: | Affinity purification |
| Background: |
| Histone H2A.X belongs to the histone H2A family, which is synthesized in G1 and S phase. It is involved in nucleosomal organization of chromatin together with other histone proteins, and is specially important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 (to form gamma-H2AFX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, which promotes DNA repair and maintains genomic stability. |
| Reactivity | Human, Monkey, Mouse, Rat |
| Tested applications | IF FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 15 kDa |
| Recommended Dilutions |
IF 1:50
FC 1:50
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2AX The antibody was conjugated to Alexa Fluor® 647 under optimal conditions with an F/P ratio of 2-5 The Alexa Fluor® 647 dye is maximally excited by red light (eg 633 nm H |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | H2A.X, H2A/X, H2AX |
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