Phospho-RSK1/RSK2/RSK3-Ser380 Rabbit Monoclonal Antibody
No Size Price Availability  
ARMF047P-21 50ul 1500.00 In Stock
ARMF047P-21 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 6195/6196/6197
Isotype: IgG Swiss Prot: Q15418/P51812/Q15349
purity: Affinity purification
Background:
The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains (1) and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs) (2). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363, and Thr573, are important for kinase activation (3). RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters (3).
Reactivity Human, Monkey, Mouse, Rat
Tested applications WB
Clonality Monoclonal Antibody
Calculated MW 90 kDa
Recommended Dilutions
WB 1:1000
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser380 of human p90RSK
Storage Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Synonym /
This product is for research use only, not for diagnostic or therapeutic use!

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