Source: | Mouse | Gene Id: | 7299 |
Isotype: | IgG2a | Swiss Prot: | P14679 |
purity: | Affinity purification |
Background: |
Tyrosinase, found in the membrane of melanosomes (1), is a key enzyme in the biosynthesis of melanin pigments (1,2). It is a melanocyte differentiation antigen and is expressed in normal melanocytes and malignant melanomas (1,3). Tyrosinase is implicated to be an antigen target for melanoma vaccines (1). |
Reactivity | Human |
Tested applications | IHC |
Clonality | Monoclonal Antibody |
Calculated MW | 70-80 kDa |
Recommended Dilutions |
IHC 1:200
|
Immunogen | A purified recombinant tyrosinase |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | OCA1A, OCAIA, SHEP3 |
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