| Source: | Mouse | Gene Id: | 7299 | 
| Isotype: | IgG2a | Swiss Prot: | P14679 | 
| purity: | Affinity purification | 
| Background: | 
| Tyrosinase, found in the membrane of melanosomes (1), is a key enzyme in the biosynthesis of melanin pigments (1,2). It is a melanocyte differentiation antigen and is expressed in normal melanocytes and malignant melanomas (1,3). Tyrosinase is implicated to be an antigen target for melanoma vaccines (1). | 
| Reactivity | Human | 
| Tested applications | IHC | 
| Clonality | Monoclonal Antibody | 
| Calculated MW | 70-80 kDa | 
| Recommended Dilutions | IHC 1:200 | 
| Immunogen | A purified recombinant tyrosinase | 
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | OCA1A, OCAIA, SHEP3 | 
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