Source: | Mouse | Gene Id: | 4792 |
Isotype: | IgG1 | Swiss Prot: | P25963 |
purity: | Affinity purification |
Background: |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |
Reactivity | Bovine, Guinea pig, Human, Monkey, Mouse, Pig, Rat |
Tested applications | FC |
Clonality | Monoclonal Antibody |
Calculated MW | 39 kDa |
Recommended Dilutions |
FC 1:50
|
Immunogen | A GST-IκBα fusion protein corresponding the amino terminus of human IκBα protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | IKBA, MAD-3, NFKBI |
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