| Source: | Mouse | Gene Id: | 4792 | 
| Isotype: | IgG1 | Swiss Prot: | P25963 | 
| purity: | Affinity purification | 
| Background: | 
| This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. | 
| Reactivity | Bovine, Guinea pig, Human, Monkey, Mouse, Pig, Rat | 
| Tested applications | FC | 
| Clonality | Monoclonal Antibody | 
| Calculated MW | 39 kDa | 
| Recommended Dilutions | FC 1:50 | 
| Immunogen | A GST-IκBα fusion protein corresponding the amino terminus of human IκBα protein | 
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. | 
| Synonym | IKBA, MAD-3, NFKBI | 
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