Source: | Rabbit | Gene Id: | 2597 |
Isotype: | / | Swiss Prot: | P04406 |
purity: | Affinity purification |
Background: |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the phosphorylation of glyceraldehyde-3-phosphate during glycolysis. Though differentially expressed from tissue to tissue (1), GAPDH is thought to be a constitutively expressed housekeeping protein. For this reason, GAPDH mRNA and protein levels are often measured as controls in experiments quantifying specific changes in expression of other targets. Recent work has elucidated roles for GAPDH in apoptosis (2), gene expression (3), and nuclear transport (4). GAPDH may also play a role in neurodegenerative pathologies such as Huntington and Alzheimer's diseases (4,5). |
Reactivity | Human, Monkey, Mouse, Rat |
Tested applications | WB |
Clonality | Monoclonal Antibody |
Calculated MW | 37 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic peptide corresponding to residues near the carboxy terminus of human GAPDH protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | GAPDH, G3PD, GAPD, MGC88685 |
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