| No | Size | Price | Availability | |
| ARM3872-21C | 50ul | 1500.00 | In Stock |  |
| ARM3872-21C | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 3872 |
| Isotype: | IgG | Swiss Prot: | Q04695 |
| purity: | Affinity purification |
| Background: |
| Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as research biomarkers (1). Research studies have shown that mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | IF FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 49 kDa |
| Recommended Dilutions |
IF 1:50
FC 1:50
|
| Immunogen | A synthetic peptide corresponding to amino acids near the carboxy terminus of human keratin 17 protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | K17, PC, PC2, PCHC1 |
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