| No | Size | Price | Availability | |
| ARM4747-23C | 50ul | 1500.00 | In Stock |  |
| ARM4747-23C | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 4747 |
| Isotype: | IgG | Swiss Prot: | P07196 |
| purity: | Affinity purification |
| Background: |
| Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq |
| Reactivity | Mouse, Rat |
| Tested applications | IF |
| Clonality | Monoclonal Antibody |
| Calculated MW | 62 kDa |
| Recommended Dilutions |
IF 1:50
|
| Immunogen | A synthetic peptide surrounding Glu450 of human Neurofilament-L protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CMT1F, CMT2E, FLJ53642, NF-L, NF68, NFL |
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