Source: | Mouse | Gene Id: | 5111 |
Isotype: | IgG2a | Swiss Prot: | P12004 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. |
Reactivity | Bovine, Human, Monkey, Mouse, Pig, Rat |
Tested applications | FC |
Clonality | Monoclonal Antibody |
Calculated MW | 36 kDa |
Recommended Dilutions |
FC 1:50
|
Immunogen | A recombinant Protein A-PCNA fusion protein obtained from pC2T |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MGC8367 |
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