Source: | Rabbit | Gene Id: | 6714 |
Isotype: | IgG | Swiss Prot: | P12931 |
purity: | Affinity purification |
Background: |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
Reactivity | Human, Mouse, Rat |
Tested applications | WB |
Clonality | Monoclonal Antibody |
Calculated MW | 60 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A recombinant fusion protein corresponding to residues 1-110 of human Src protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | ASV, SRC1, c-SRC, p60-Src |
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