| No | Size | Price | Availability | |
| ARM5159-21C | 50ul | 1500.00 | In Stock |  |
| ARM5159-21C | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 5159 |
| Isotype: | IgG | Swiss Prot: | P09619 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB |
| Clonality | Monoclonal Antibody |
| Calculated MW | 190 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A GST fusion protein containing a carboxy-terminal fragment of human PDGF receptor β protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CD140B, JTK12, PDGF-R-beta, PDGFR, PDGFR1 |
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