Source: | Rabbit | Gene Id: | 367 |
Isotype: | IgG | Swiss Prot: | P10275 |
purity: | Affinity purification |
Background: |
Androgen receptor (AR), a zinc finger transcription factor belonging to the nuclear receptor superfamily, is activated by phosphorylation and dimerization upon ligand binding (1). This promotes nuclear localization and binding of AR to androgen response elements in androgen target genes. Research studies have shown that AR plays a crucial role in several stages of male development and the progression of prostate cancer (2,3). |
Reactivity | Human |
Tested applications | IF FC |
Clonality | Monoclonal Antibody |
Calculated MW | 110 kDa |
Recommended Dilutions |
IF 1:50
FC 1:50
|
Immunogen | A recombinant protein corresponding to residues near the amino terminal region of human androgen receptor protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | KD, AIS, TFM, DHTR, SBMA, HYSP1, NR3C4, SMAX1, HUMARA |
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