| No | Size | Price | Availability | |
| ARMF025P-22 | 50ul | 1500.00 | In Stock |  |
| ARMF025P-22 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 2534/3055/3932/4067/6714/7525 |
| Isotype: | IgG | Swiss Prot: | P06241/P08631/P06239/P07948/P12931/P07947 |
| purity: | Affinity purification |
| Background: |
| The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1). Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2). |
| Reactivity | Human, Monkey, Mouse, Rat |
| Tested applications | WB IP |
| Clonality | Monoclonal Antibody |
| Calculated MW | 60 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Tyr416 of human Src protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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