| No | Size | Price | Availability | |
| ARM52231-21 | 50ul | 1500.00 | In Stock |  |
| ARM52231-21 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 52231(Mouse) |
| Isotype: | IgG | Swiss Prot: | Q80UU1 |
| purity: | Affinity purification |
| Background: |
| Mitochondria are membrane-bound subcellular organelles critical to many functions in eukaryotic cells (1). Several mechanisms have been found to play a role in mitochondria quality control (2). A recent study identified mitochondria-associated protein degradation as one such mechanism (1,2). The study showed that VMS1 (VCP/Cdc48-associated mitochondrial stress-responsive) interacts with VCP/Cdc48 and Npl4, two components in the endoplasmic reticulum-associated protein degradation pathway, and mediates the degradation of damaged mitochondrial proteins under stress conditions (1). Defective VMS1 compromises mitochondrial functions and cell viability (1). |
| Reactivity | Mouse |
| Tested applications | WB |
| Clonality | Monoclonal Antibody |
| Calculated MW | 100 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic peptide corresponding to residues surrounding Gly332 of mouse VMS1 protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | / |
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