Source: | Rabbit | Gene Id: | 5156 |
Isotype: | IgG | Swiss Prot: | P16234 |
purity: | Affinity purification |
Background: |
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provided by RefSeq |
Reactivity | Human |
Tested applications | FC |
Clonality | Monoclonal Antibody |
Calculated MW | 190 kDa |
Recommended Dilutions |
FC 1:50
|
Immunogen | A recombinant protein corresponding to the PDGF receptor α extracellular domain |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CD140A, MGC74795, PDGFR2, Rhe-PDGFRA |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.