MLST8 Rabbit Monoclonal Antibody (Sepharose Bead Conjugate)
No Size Price Availability  
ARM64223-22C 50ul 1500.00 In Stock
ARM64223-22C 100ul 2000.00 In Stock
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Source: Rabbit Gene Id: 64223
Isotype: / Swiss Prot: Q9BVC4
purity: Affinity purification
Background:
Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian Target of Rapamycin (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals (1). mTOR is a large protein kinase with two different complexes. One complex contains mTOR, GβL, and raptor, which is a target of rapamycin. The other complex, insensitive to rapamycin, includes mTOR, GβL, and rictor (1). GβL associates with the kinase domain of mTOR and stimulates mTOR kinase activity (2). A reduction in GβL expression has been shown to decrease in vivo phosphorylation of S6K1 (2).
Reactivity /
Tested applications IP
Clonality Monoclonal Antibody
Calculated MW 36 kDa
Recommended Dilutions
Immunogen /
Storage Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles.
Synonym GBL, LST8, MGC111011, POP3, WAT1
This product is for research use only, not for diagnostic or therapeutic use!

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