Source: | Rabbit | Gene Id: | 3014 |
Isotype: | IgG | Swiss Prot: | P16104 |
purity: | Affinity purification |
Background: |
Histone H2A.X belongs to the histone H2A family, which is synthesized in G1 and S phase. It is involved in nucleosomal organization of chromatin together with other histone proteins, and is specially important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 (to form gamma-H2AFX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, which promotes DNA repair and maintains genomic stability. |
Reactivity | Human, Monkey, Mouse, Rat |
Tested applications | FC |
Clonality | Monoclonal Antibody |
Calculated MW | 15 kDa |
Recommended Dilutions |
FC 1:50
|
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser139 of human H2AX protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | H2A.X, H2A/X, H2AX |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.