Source: | Rabbit | Gene Id: | 3815 |
Isotype: | IgG | Swiss Prot: | P10721 |
purity: | Affinity purification |
Background: |
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |
Reactivity | Human, Mouse |
Tested applications | WB |
Clonality | Monoclonal Antibody |
Calculated MW | 120, 145 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic peptide corresponding to residues surrounding Tyr703 of human c-Kit protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | C-Kit, CD117, PBT, SCFR |
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