Source: | Mouse | Gene Id: | 5604 |
Isotype: | IgG2a | Swiss Prot: | P07288 |
purity: | Affinity purification |
Background: |
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq |
Reactivity | Human, Monkey, Mouse, Rat |
Tested applications | WB |
Clonality | Monoclonal Antibody |
Calculated MW | 45 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | Full length MEK1 proteins |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MAPKK1, MEK1, MKK1, PRKMK1 |
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