Source: | Rabbit | Gene Id: | 1104 |
Isotype: | IgG | Swiss Prot: | P18754 |
purity: | Affinity purification |
Background: |
CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1. |
Reactivity | Human |
Tested applications | WB |
Clonality | Monoclonal Antibody |
Calculated MW | 45 kDa |
Recommended Dilutions |
WB 1:1000
|
Immunogen | A synthetic peptide corresponding to residues surrounding Ser11 of human RCC1 protein |
Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CHC1, RCC1-I, SNHG3-RCC1 |
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