| Source: | Rabbit | Gene Id: | 79923 |
| Isotype: | IgG | Swiss Prot: | Q9H9S0 |
| purity: | Affinity purification |
| Background: |
| Nanog is a homeodomain-containing transcription factor that is essential for the maintenance of pluripotency and self renewal in embryonic stem cells (1). Nanog expression is controlled by a network of factors including Sox2 and the key pluripotency regulator Oct-4 (1). Recent advances in somatic cell reprogramming have utilized viral expression of combinations of transcription factors including nanog, Oct-4, Sox2, KLF4, c-Myc, and LIN28 (2,3). |
| Reactivity | Human |
| Tested applications | IF FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 42 kDa |
| Recommended Dilutions |
IF 1:50
FC 1:50
|
| Immunogen | A synthetic peptide corresponding to residues near the amino terminus of human nanog protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | Nanog, Nanog homeobox, Homeobox protein NANOG, hNanog |
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