| No | Size | Price | Availability | |
| ARM1965P-21C | 50ul | 1500.00 | In Stock |  |
| ARM1965P-21C | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 1965 |
| Isotype: | IgG | Swiss Prot: | P05198 |
| purity: | Affinity purification |
| Background: |
| The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S28), and the 52-kD EIF2-gamma subunit (EIF2S3). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha. |
| Reactivity | D. melanogaster, Human, Monkey, Mouse, Rat |
| Tested applications | WB |
| Clonality | Monoclonal Antibody |
| Calculated MW | 38 kDa |
| Recommended Dilutions |
WB 1:1000
|
| Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser51 of human eIF2α protein |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | EIF2, EIF-2, EIF2A, EIF-2A, EIF-2alpha |
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