| No | Size | Price | Availability | |
| AMM4792-22S | 50ul | 1500.00 | In Stock |  |
| AMM4792-22S | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 4792 |
| Isotype: | IgG1 | Swiss Prot: | P25963 |
| purity: | Affinity purification |
| Background: |
| This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. |
| Reactivity | Bovine, Guinea pig, Human, Monkey, Mouse, Pig, Rat |
| Tested applications | WB IHC IP IF FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 39 kDa |
| Recommended Dilutions |
WB 1:1000
IHC 1:50
IF 1:125
FC 1:800
|
| Immunogen | A GST-IκBα fusion protein corresponding the amino-terminus of human IκBα |
| Storage | Store at -20°C in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | IKBA, MAD-3, NFKBI |
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